Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational  Age Interval

Dascau, Voicu; Furau, Gheorghe; Pilat, Luminita; Onel, Cristina; Puschita, Maria

Voicu Dascau, Gheorghe Furau, Luminita Pilat, Cristina Onel, Maria Puschita

Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval

Abstract:

The aim of our study was to assess the predictive values for hypertensive complications of pregnancy of the multiples of median (MoM) of serum pregnancy associated plasma protein A (PAPP-A), measured in 128 pregnant patients between 11 and 14 weeks gestational age. The 5th and the 10th percentile for MoM PAPP-A were 0.27 and 0.33, respectively. The detection rate for pregnancy induced hypertension, mild preeclampsia, severe preeclampsia, all preeclampsia and all hypertensive complications was 0%, 9.09%, 0%, 7.69%, and 6.25% for MoM PAPP-A below the 5th percentile (for a false positive rate of 5%), and 33.33%, 9.09%, 0%, 7.69%, and 12.5% for MoM PAPP-A below the 10th percentile (for a false positive rate of 10%), respectively. The specificity ranged from 89.57% to 95.73%, the positive predictive value from 0% to 16.67%, and the negative predictive value from 87.70% to 98.36%.

Keywords:
pregnancy; preeclampsia; screening; detection rate; PAPP-A

Issue: 2020, Volume 71, Issue 2

Pages: 262-266

Publication date: 2020/3/3

https://doi.org/10.37358/RC.20.2.7924

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
DASCAU, V., FURAU, G., PILAT, L., ONEL, C., PUSCHITA, M., Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval, Rev. Chim., 71(2), 2020, 262-266.

Vancouver
Dascau V, Furau G, Pilat L, Onel C, Puschita M. Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval. Rev. Chim.[internet]. 2020 Feb;71(2):262-266. Available from: https://doi.org/10.37358/RC.20.2.7924

APA 6th edition
Dascau, V., Furau, G., Pilat, L., Onel, C. & Puschita, M. (2020). Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval. Revista de Chimie, 71(2), 262-266. https://doi.org/10.37358/RC.20.2.7924

Harvard
Dascau, V., Furau, G., Pilat, L., Onel, C., Puschita, M. (2020). 'Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval', Revista de Chimie, 71(2), pp. 262-266. https://doi.org/10.37358/RC.20.2.7924

IEEE
V. Dascau, G. Furau, L. Pilat, C. Onel, M. Puschita, "Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval". Revista de Chimie, vol. 71, no. 2, pp. 262-266, 2020. [online]. https://doi.org/10.37358/RC.20.2.7924

Text
Voicu Dascau, Gheorghe Furau, Luminita Pilat, Cristina Onel, Maria Puschita,
Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval,
Revista de Chimie,
Volume 71, Issue 2,
2020,
Pages 262-266,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.2.7924.
(https://revistadechimie.ro/Articles.asp?ID=7924)
Keywords: pregnancy; preeclampsia; screening; detection rate; PAPP-A

RIS
TY - JOUR
T1 - Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval
A1 - Dascau, Voicu
A2 - Furau, Gheorghe
A3 - Pilat, Luminita
A4 - Onel, Cristina
A5 - Puschita, Maria
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 2
SP - 262
EP - 266
UR - https://doi.org/10.37358/RC.20.2.7924
KW - pregnancy
KW - preeclampsia
KW - screening
KW - detection rate
KW - PAPP-A
ER -

BibTex
@article{RevCh2020P262,
author = {Dascau Voicu and Furau Gheorghe and Pilat Luminita and Onel Cristina and Puschita Maria},
title = {Screening for Hypertensive Pregnancy Complications through Maternal Serum PAPP-A 5th and 10th Percentiles during the 11-14 Weeks Gestational Age Interval},
journal = {Revista de Chimie},
volume = {71},
number = {2},
pages = {262-266},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.2.7924},
url = {https://revistadechimie.ro/Articles.asp?ID=7924}
}

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