Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples

Buleandra, Mihaela; Moldovan, Zenovia; Badea, Irinel Adriana; David, Iulia Gabriela; Popa, Dana Elena; Oprea, Eliza; Caglar, Tugce Ayca Tekiner; Basaga, Selma Huveyda

Mihaela Buleandra, Zenovia Moldovan, Irinel Adriana Badea, Iulia Gabriela David, Dana Elena Popa, Eliza Oprea, Tugce Ayca Tekiner Caglar, Selma Huveyda Basaga

Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples

Abstract:

Millefolii herba is an available product on the Romanian market as mixture of stems, leaves and flowers of Achillea millefolium L. There were established its volatile compounds profile, total polyphenolic content (TPC), antioxidant capacity and effects on HCT 116 cell viability and programmed cell death. The infusion, hydroalcoholic extract and hydrodistillated essential oil were studied. A comparative analysis using static headspace (HS) and hydro-distillation (HD) GC/MS of the volatile components from Millefolii herba was realized: the essential oil contains chamazulene as the principal component (37.1%), while 1,8-cineole (46.8%) is the main constituent of headspace volatiles. The highest antioxidant capacity was found in essential oil, compared with hydroalcoholic extract, infusion and ascorbic acid. Yarrow hydroalcoholic extract reduced the HCT 116 cell viability and induced the apoptotic cell death in a dose and time dependent manner.

Keywords:
Achillea millefolium L.; GC/MS; total polyphenolic content; colon carcinoma cell viability

Issue: 2020, Volume 71, Issue 3

Pages: 69-78

Publication date: 2020/4/3

https://doi.org/10.37358/RC.20.3.7975

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BULEANDRA, M., MOLDOVAN, Z., BADEA, I.A., DAVID, I.G., POPA, D.E., OPREA, E., CAGLAR, T.A.T., BASAGA, S.H., Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples, Rev. Chim., 71(3), 2020, 69-78.

Vancouver
Buleandra M, Moldovan Z, Badea IA, David IG, Popa DE, Oprea E, Caglar TAT, Basaga SH. Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples. Rev. Chim.[internet]. 2020 Mar;71(3):69-78. Available from: https://doi.org/10.37358/RC.20.3.7975

APA 6th edition
Buleandra, M., Moldovan, Z., Badea, I.A., David, I.G., Popa, D.E., Oprea, E., Caglar, T.A.T. & Basaga, S.H. (2020). Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples. Revista de Chimie, 71(3), 69-78. https://doi.org/10.37358/RC.20.3.7975

Harvard
Buleandra, M., Moldovan, Z., Badea, I.A., David, I.G., Popa, D.E., Oprea, E., Caglar, T.A.T., Basaga, S.H. (2020). 'Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples', Revista de Chimie, 71(3), pp. 69-78. https://doi.org/10.37358/RC.20.3.7975

IEEE
M. Buleandra, Z. Moldovan, I.A. Badea, I.G. David, D.E. Popa, E. Oprea, T.A.T. Caglar, S.H. Basaga, "Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples". Revista de Chimie, vol. 71, no. 3, pp. 69-78, 2020. [online]. https://doi.org/10.37358/RC.20.3.7975

Text
Mihaela Buleandra, Zenovia Moldovan, Irinel Adriana Badea, Iulia Gabriela David, Dana Elena Popa, Eliza Oprea, Tugce Ayca Tekiner Caglar, Selma Huveyda Basaga,
Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples,
Revista de Chimie,
Volume 71, Issue 3,
2020,
Pages 69-78,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.3.7975.
(https://revistadechimie.ro/Articles.asp?ID=7975)
Keywords: Achillea millefolium L.; GC/MS; total polyphenolic content; colon carcinoma cell viability

RIS
TY - JOUR
T1 - Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples
A1 - Buleandra, Mihaela
A2 - Moldovan, Zenovia
A3 - Badea, Irinel Adriana
A4 - David, Iulia Gabriela
A5 - Popa, Dana Elena
A6 - Oprea, Eliza
A7 - Caglar, Tugce Ayca Tekiner
A8 - Basaga, Selma Huveyda
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 3
SP - 69
EP - 78
UR - https://doi.org/10.37358/RC.20.3.7975
KW - Achillea millefolium L.
KW - GC/MS
KW - total polyphenolic content
KW - colon carcinoma cell viability
ER -

BibTex
@article{RevCh2020P69,
author = {Buleandra Mihaela and Moldovan Zenovia and Badea Irinel Adriana and David Iulia Gabriela and Popa Dana Elena and Oprea Eliza and Caglar Tugce Ayca Tekiner and Basaga Selma Huveyda},
title = {Comparative Assessment of the Volatile Profile, Antioxidant Capacity and Cytotoxic Potential of Different Preparation of Millefolli Herba Samples},
journal = {Revista de Chimie},
volume = {71},
number = {3},
pages = {69-78},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.3.7975},
url = {https://revistadechimie.ro/Articles.asp?ID=7975}
}

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