Considerations on the Influence of Zinc on Infectious Diseases  in Children

Negrut, Nicoleta; Rus, Marius; Pantis, Carmen; Maghiar, Octavian; Cseppento, Carmen Delia Nistor; Uivarosan, Diana; Stanescu, Ana Maria Alexandra; Spinu, Dan Arsenie; Fratila, Ovidiu; Bungau, Simona

Nicoleta Negrut, Marius Rus, Carmen Pantis, Octavian Maghiar, Carmen Delia Nistor Cseppento, Diana Uivarosan, Ana Maria Alexandra Stanescu, Dan Arsenie Spinu, Ovidiu Fratila, Simona Bungau

Considerations on the Influence of Zinc on Infectious Diseases in Children

Abstract:

Zinc modulates the human body defence against infections. Mild and medium deficiency in this mineral appears usually sub-clinically, being mistaken for other diseases, but the severe form can be fatal. The purpose of the study was to determine the plasma zinc concentration (PZC) for the most common infectious pathology in children. Zinc was measured in plasma using direct colorimetric assay based on the 5-Br-PAPS method (CV% 0.98-4.64%). In the paediatric patients, 0-3 years old, the PZC values were 15.20±1.37 μmol/L, with limits ranging between 13.05-20.6 μmol/L, the values falling within normal limits and proving the absence of zinc deficiency in the investigated population. During 3 years of follow up, 137 healthy children presented low values of plasma zinc concentration if they had acute lower respiratory infections, acute otitis media or giardiasis in past medical history. There were not found significant differences in case of children with viral or bacterial acute diarrheal diseases or viral exanthemas. In the present study, the children exposed to severe, complicated or chronic forms of infectious diseases were predisposed to low plasma zinc concentrations.

Keywords:
plasma zinc concentration; infectious diseases; children

Issue: 2020, Volume 71, Issue 4

Pages: 571-580

Publication date: 2020/5/5

https://doi.org/10.37358/RC.20.4.8098

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
NEGRUT, N., RUS, M., PANTIS, C., MAGHIAR, O., CSEPPENTO, C.D.N., UIVAROSAN, D., STANESCU, A.M.A., SPINU, D.A., FRATILA, O., BUNGAU, S., Considerations on the Influence of Zinc on Infectious Diseases in Children, Rev. Chim., 71(4), 2020, 571-580.

Vancouver
Negrut N, Rus M, Pantis C, Maghiar O, Cseppento CDN, Uivarosan D, Stanescu AMA, Spinu DA, Fratila O, Bungau S. Considerations on the Influence of Zinc on Infectious Diseases in Children. Rev. Chim.[internet]. 2020 Apr;71(4):571-580. Available from: https://doi.org/10.37358/RC.20.4.8098

APA 6th edition
Negrut, N., Rus, M., Pantis, C., Maghiar, O., Cseppento, C.D.N., Uivarosan, D.,... Bungau, S. (2020). Considerations on the Influence of Zinc on Infectious Diseases in Children. Revista de Chimie, 71(4), 571-580. https://doi.org/10.37358/RC.20.4.8098

Harvard
Negrut, N., Rus, M., Pantis, C., Maghiar, O., Cseppento, C.D.N., Uivarosan, D., Stanescu, A.M.A., Spinu, D.A., Fratila, O., Bungau, S. (2020). 'Considerations on the Influence of Zinc on Infectious Diseases in Children', Revista de Chimie, 71(4), pp. 571-580. https://doi.org/10.37358/RC.20.4.8098

IEEE
N. Negrut, M. Rus, C. Pantis, O. Maghiar, C.D.N. Cseppento, D. Uivarosan, A.M.A. Stanescu, D.A. Spinu, O. Fratila, S. Bungau, "Considerations on the Influence of Zinc on Infectious Diseases in Children". Revista de Chimie, vol. 71, no. 4, pp. 571-580, 2020. [online]. https://doi.org/10.37358/RC.20.4.8098

Text
Nicoleta Negrut, Marius Rus, Carmen Pantis, Octavian Maghiar, Carmen Delia Nistor Cseppento, Diana Uivarosan, Ana Maria Alexandra Stanescu, Dan Arsenie Spinu, Ovidiu Fratila, Simona Bungau,
Considerations on the Influence of Zinc on Infectious Diseases in Children,
Revista de Chimie,
Volume 71, Issue 4,
2020,
Pages 571-580,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.4.8098.
(https://revistadechimie.ro/Articles.asp?ID=8098)
Keywords: plasma zinc concentration; infectious diseases; children

RIS
TY - JOUR
T1 - Considerations on the Influence of Zinc on Infectious Diseases in Children
A1 - Negrut, Nicoleta
A2 - Rus, Marius
A3 - Pantis, Carmen
A4 - Maghiar, Octavian
A5 - Cseppento, Carmen Delia Nistor
A6 - Uivarosan, Diana
A7 - Stanescu, Ana Maria Alexandra
A8 - Spinu, Dan Arsenie
A9 - Fratila, Ovidiu
A10 - Bungau, Simona
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 4
SP - 571
EP - 580
UR - https://doi.org/10.37358/RC.20.4.8098
KW - plasma zinc concentration
KW - infectious diseases
KW - children
ER -

BibTex
@article{RevCh2020P571,
author = {Negrut Nicoleta and Rus Marius and Pantis Carmen and Maghiar Octavian and Cseppento Carmen Delia Nistor and Uivarosan Diana and Stanescu Ana Maria Alexandra and Spinu Dan Arsenie and Fratila Ovidiu and Bungau Simona},
title = {Considerations on the Influence of Zinc on Infectious Diseases in Children},
journal = {Revista de Chimie},
volume = {71},
number = {4},
pages = {571-580},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.4.8098},
url = {https://revistadechimie.ro/Articles.asp?ID=8098}
}

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