The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism

Crisan, Adrian; Mitu, Ovidiu; Costache, Irina Iuliana; Miftode, Radu; Haba, Cristian Mihai Stefan; Mitu, Ivona; Dimitriu, Daniela-Cristina; Petris, Antoniu Octavian

Adrian Crisan, Ovidiu Mitu, Irina Iuliana Costache, Radu Miftode, Cristian Mihai Stefan Haba, Ivona Mitu, Daniela-Cristina Dimitriu, Antoniu Octavian Petris

The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism

Abstract:

Assessing the biochemical parameters in patients with pulmonary embolism (PE), deep vein thrombosis (DVT) or both brings complimentary information for the cardiovascular (CV) and death risk stratification. The purpose of the study was to evaluate the association between biochemical parameters and PE, DVT or both. The study was prospective, conducted over a 12-month period and included 151 patients diagnosed with PE, DVT or both pathologies. These patients were extensively analysed taking into account biochemical parameters associated with the above-mentioned pathologies. Mean age was 59.23 ± 18.22 years and 55% were women. 38.40% patients had PE, 48.30% had DVT and 13.20% had both pathologies. GFR upon admission was strongly negatively associated with age, r(148)= -0.75, p[0.01, intra-hospital death r(148)= -0.18, p=0.02 and with AST levels r(144)= -0.21, p=0.01 and positively statistically significant with the number of days of hospitalization r(8)= +0.79, p=0.0. Moreover, for one unit decrease in GFR the number of days of hospitalization decreased with 0.231. Moreover, AST correlated with intra-hospital death r(146)= 0.25, p[0.01, creatinine upon admission r(144)= 0.24, p[0.01, urea upon admission r(143)= 0.16, p=0.04 and glucose levels r(139)= 0.19, p=0.02, but negatively associated with GFR upon admission with r(144)= -0.21, p=0.01; for each one unit decrease of GFR there was an increase in AST levels by 0.21. Also there was a significant correlation between the thrombolysis therapy and the number of days of hospitalization r(151)= 0.21, p[0.01 and between positive inotropic support and intra-hospital death with r(151)= 0.27, p[0.01. In patients with PE, DVT or both, renal function, AST levels and the number of days of hospitalization were associated with an increased risk of death, especially in patients with PE ± DVT.

Keywords:
biochemical parameters; pulmonary embolism; deep vein thrombosis; venous thrombembolism

Issue: 2020, Volume 71, Issue 4

Pages: 594-600

Publication date: 2020/5/5

https://doi.org/10.37358/RC.20.4.8100

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CRISAN, A., MITU, O., COSTACHE, I.I., MIFTODE, R., HABA, C.M.S., MITU, I., DIMITRIU, D., PETRIS, A.O., The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism, Rev. Chim., 71(4), 2020, 594-600.

Vancouver
Crisan A, Mitu O, Costache II, Miftode R, Haba CMS, Mitu I, Dimitriu D, Petris AO. The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism. Rev. Chim.[internet]. 2020 Apr;71(4):594-600. Available from: https://doi.org/10.37358/RC.20.4.8100

APA 6th edition
Crisan, A., Mitu, O., Costache, I.I., Miftode, R., Haba, C.M.S., Mitu, I., Dimitriu, D. & Petris, A.O. (2020). The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism. Revista de Chimie, 71(4), 594-600. https://doi.org/10.37358/RC.20.4.8100

Harvard
Crisan, A., Mitu, O., Costache, I.I., Miftode, R., Haba, C.M.S., Mitu, I., Dimitriu, D., Petris, A.O. (2020). 'The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism', Revista de Chimie, 71(4), pp. 594-600. https://doi.org/10.37358/RC.20.4.8100

IEEE
A. Crisan, O. Mitu, I.I. Costache, R. Miftode, C.M.S. Haba, I. Mitu, D. Dimitriu, A.O. Petris, "The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism". Revista de Chimie, vol. 71, no. 4, pp. 594-600, 2020. [online]. https://doi.org/10.37358/RC.20.4.8100

Text
Adrian Crisan, Ovidiu Mitu, Irina Iuliana Costache, Radu Miftode, Cristian Mihai Stefan Haba, Ivona Mitu, Daniela-Cristina Dimitriu, Antoniu Octavian Petris,
The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism,
Revista de Chimie,
Volume 71, Issue 4,
2020,
Pages 594-600,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.4.8100.
(https://revistadechimie.ro/Articles.asp?ID=8100)
Keywords: biochemical parameters; pulmonary embolism; deep vein thrombosis; venous thrombembolism

RIS
TY - JOUR
T1 - The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism
A1 - Crisan, Adrian
A2 - Mitu, Ovidiu
A3 - Costache, Irina Iuliana
A4 - Miftode, Radu
A5 - Haba, Cristian Mihai Stefan
A6 - Mitu, Ivona
A7 - Dimitriu, Daniela-Cristina
A8 - Petris, Antoniu Octavian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 4
SP - 594
EP - 600
UR - https://doi.org/10.37358/RC.20.4.8100
KW - biochemical parameters
KW - pulmonary embolism
KW - deep vein thrombosis
KW - venous thrombembolism
ER -

BibTex
@article{RevCh2020P594,
author = {Crisan Adrian and Mitu Ovidiu and Costache Irina Iuliana and Miftode Radu and Haba Cristian Mihai Stefan and Mitu Ivona and Dimitriu Daniela-Cristina and Petris Antoniu Octavian},
title = {The Assessment of Biochemical Parameters in Patients with Venous Thromboembolism},
journal = {Revista de Chimie},
volume = {71},
number = {4},
pages = {594-600},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.4.8100},
url = {https://revistadechimie.ro/Articles.asp?ID=8100}
}

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