Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of  Antioxidant and Cytotoxic Activity

Racoviceanu, Roxana; Farcas, Claudia; Ghiulai, Roxana; Sima, Laurentiu Vasile; Dragoi, Razvan Gabriel; Trandafirescu, Cristina; Antal, Diana; Mioc, Marius; Dehelean, Cristina; Soica, Codruta

Roxana Racoviceanu, Claudia Farcas, Roxana Ghiulai, Laurentiu Vasile Sima, Razvan Gabriel Dragoi, Cristina Trandafirescu, Diana Antal, Marius Mioc, Cristina Dehelean, Codruta Soica

Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity

Abstract:

Armoracia rusticana - horseradish is a well-known vegetable used from ancient times and consumed nowadays more for its taste than its pharmacological properties, even though it proved to be a good agent in fighting several health problems. This study focuses on a comparative assessment of several horseradish hydro-alcoholic extracts, obtained from roots and sprouts, respectively, mainly evaluating the antioxidant activity but also a potential cytotoxic effect. The DPPH evaluation revealed that horseradish extracts made from roots or sprouts exhibit a strong antioxidant activity compared to the ascorbic acid used as etalon. The in vitro evaluation established that a significant inhibitory effect on cell viability and morphology of MDA-MB-231 - breast adenocarcinoma cell line was displayed by the hydroalcoholic extracts in a dose-dependent manner.

Keywords:
Armoraciarusticana; extract; antioxidantactivity; MDA-MB-231

Issue: 2020, Volume 71, Issue 5

Pages: 201-210

Publication date: 2020/5/29

https://doi.org/10.37358/RC.20.5.8128

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
RACOVICEANU, R., FARCAS, C., GHIULAI, R., SIMA, L.V., DRAGOI, R.G., TRANDAFIRESCU, C., ANTAL, D., MIOC, M., DEHELEAN, C., SOICA, C., Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity, Rev. Chim., 71(5), 2020, 201-210.

Vancouver
Racoviceanu R, Farcas C, Ghiulai R, Sima LV, Dragoi RG, Trandafirescu C, Antal D, Mioc M, Dehelean C, Soica C. Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity. Rev. Chim.[internet]. 2020 May;71(5):201-210. Available from: https://doi.org/10.37358/RC.20.5.8128

APA 6th edition
Racoviceanu, R., Farcas, C., Ghiulai, R., Sima, L.V., Dragoi, R.G., Trandafirescu, C.,... Soica, C. (2020). Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity. Revista de Chimie, 71(5), 201-210. https://doi.org/10.37358/RC.20.5.8128

Harvard
Racoviceanu, R., Farcas, C., Ghiulai, R., Sima, L.V., Dragoi, R.G., Trandafirescu, C., Antal, D., Mioc, M., Dehelean, C., Soica, C. (2020). 'Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity', Revista de Chimie, 71(5), pp. 201-210. https://doi.org/10.37358/RC.20.5.8128

IEEE
R. Racoviceanu, C. Farcas, R. Ghiulai, L.V. Sima, R.G. Dragoi, C. Trandafirescu, D. Antal, M. Mioc, C. Dehelean, C. Soica, "Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity". Revista de Chimie, vol. 71, no. 5, pp. 201-210, 2020. [online]. https://doi.org/10.37358/RC.20.5.8128

Text
Roxana Racoviceanu, Claudia Farcas, Roxana Ghiulai, Laurentiu Vasile Sima, Razvan Gabriel Dragoi, Cristina Trandafirescu, Diana Antal, Marius Mioc, Cristina Dehelean, Codruta Soica,
Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity,
Revista de Chimie,
Volume 71, Issue 5,
2020,
Pages 201-210,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.5.8128.
(https://revistadechimie.ro/Articles.asp?ID=8128)
Keywords: Armoraciarusticana; extract; antioxidantactivity; MDA-MB-231

RIS
TY - JOUR
T1 - Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity
A1 - Racoviceanu, Roxana
A2 - Farcas, Claudia
A3 - Ghiulai, Roxana
A4 - Sima, Laurentiu Vasile
A5 - Dragoi, Razvan Gabriel
A6 - Trandafirescu, Cristina
A7 - Antal, Diana
A8 - Mioc, Marius
A9 - Dehelean, Cristina
A10 - Soica, Codruta
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 5
SP - 201
EP - 210
UR - https://doi.org/10.37358/RC.20.5.8128
KW - Armoraciarusticana
KW - extract
KW - antioxidantactivity
KW - MDA-MB-231
ER -

BibTex
@article{RevCh2020P201,
author = {Racoviceanu Roxana and Farcas Claudia and Ghiulai Roxana and Sima Laurentiu Vasile and Dragoi Razvan Gabriel and Trandafirescu Cristina and Antal Diana and Mioc Marius and Dehelean Cristina and Soica Codruta},
title = {Hydro-alcoholic Extracts of Roots and Sprouts of Armoracia rusticana: Assessment of Antioxidant and Cytotoxic Activity},
journal = {Revista de Chimie},
volume = {71},
number = {5},
pages = {201-210},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.5.8128},
url = {https://revistadechimie.ro/Articles.asp?ID=8128}
}

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