Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity

Cheptea, Corina; Sunel, Valeriu; Morosanu, Cezarina; Dorohoi, Dana Ortansa

Corina Cheptea, Valeriu Sunel, Cezarina Morosanu, Dana Ortansa Dorohoi

Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity

Abstract:

In order to obtain new substances with potential biological activity dipeptide derivatives from p-aminobenzoyl-phenylglycine and p-aminobenzoyl-phenylalanine were grafted on 1,2,4-triazolic heterocycle. The new synthesized compounds belong to the group of antimetabolites, group used in medicine for treating malignant tumors. Also, it is possible to study the correlation between chemical structure and biological activity of the new compounds.

Keywords:
dipeptides derived from p-aminobenzoyl-phenylglycine and p-aminobenzoyl-phenylalanine; 1;2;4-triazole-3;4-disubstituted heterocyclic compounds; biological activity

Issue: 2020, Volume 71, Issue 5

Pages: 211-221

Publication date: 2020/5/29

https://doi.org/10.37358/RC.20.5.8129

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CHEPTEA, C., SUNEL, V., MOROSANU, C., DOROHOI, D.O., Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity, Rev. Chim., 71(5), 2020, 211-221.

Vancouver
Cheptea C, Sunel V, Morosanu C, Dorohoi DO. Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity. Rev. Chim.[internet]. 2020 May;71(5):211-221. Available from: https://doi.org/10.37358/RC.20.5.8129

APA 6th edition
Cheptea, C., Sunel, V., Morosanu, C. & Dorohoi, D.O. (2020). Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity. Revista de Chimie, 71(5), 211-221. https://doi.org/10.37358/RC.20.5.8129

Harvard
Cheptea, C., Sunel, V., Morosanu, C., Dorohoi, D.O. (2020). 'Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity', Revista de Chimie, 71(5), pp. 211-221. https://doi.org/10.37358/RC.20.5.8129

IEEE
C. Cheptea, V. Sunel, C. Morosanu, D.O. Dorohoi, "Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity". Revista de Chimie, vol. 71, no. 5, pp. 211-221, 2020. [online]. https://doi.org/10.37358/RC.20.5.8129

Text
Corina Cheptea, Valeriu Sunel, Cezarina Morosanu, Dana Ortansa Dorohoi,
Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity,
Revista de Chimie,
Volume 71, Issue 5,
2020,
Pages 211-221,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.5.8129.
(https://revistadechimie.ro/Articles.asp?ID=8129)
Keywords: dipeptides derived from p-aminobenzoyl-phenylglycine and p-aminobenzoyl-phenylalanine; 1;2;4-triazole-3;4-disubstituted heterocyclic compounds; biological activity

RIS
TY - JOUR
T1 - Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity
A1 - Cheptea, Corina
A2 - Sunel, Valeriu
A3 - Morosanu, Cezarina
A4 - Dorohoi, Dana Ortansa
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 5
SP - 211
EP - 221
UR - https://doi.org/10.37358/RC.20.5.8129
KW - dipeptides derived from p-aminobenzoyl-phenylglycine and p-aminobenzoyl-phenylalanine
KW - 1
KW - 2
KW - 4-triazole-3
KW - 4-disubstituted heterocyclic compounds
KW - biological activity
ER -

BibTex
@article{RevCh2020P211,
author = {Cheptea Corina and Sunel Valeriu and Morosanu Cezarina and Dorohoi Dana Ortansa},
title = {Derivatives of 1,2,4-Triazole-3,4-Disubstituted Based on Aminoacids with Potential Biological Activity},
journal = {Revista de Chimie},
volume = {71},
number = {5},
pages = {211-221},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.5.8129},
url = {https://revistadechimie.ro/Articles.asp?ID=8129}
}

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