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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2020, Volume 71, Issue 5, 400-408

https://doi.org/10.37358/RC.20.5.8150

Tati Suhartati, Eka Epriyanti, Inggit Borisha, Yandri, Jhons F. Suwandi, Suripto D. Yuwono, Hardoko I. Qudus, Sutopo Hadi

In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus

Abstract:

The derivative of flavonoid compounds, artocarpin (1) and artonin M (2), were isolated from the root wood of Artocarpus altilis and from the root bark of A. kemando, respectively. Both plants originated from Lampung, Indonesia. The structure of the two compounds has been carefully determined by physical method and spectroscopy techniques of UV, IR, and NMR. The in vivo antimalarial test of artocarpin showed very good Plasmodium activity in female mice, with ED50 value of 34.88 mg/kg body weight (kgBW), whereas the in vitro antimalarial test of artonin M showed very strong activity with IC50 of 0.3 μg/mL (5.967 x 10-7 M).
Keywords:
antimalarial; artocarpin; artonin M; A. altilis; A. kemando

Issue: 2020, Volume 71, Issue 5
Pages: 400-408
Publication date: 2020/5/29
https://doi.org/10.37358/RC.20.5.8150
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SUHARTATI, T., EPRIYANTI, E., BORISHA, I., YANDRI, , SUWANDI, J.F., YUWONO, S.D., QUDUS, H.I., HADI, S., In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus, Rev. Chim., 71(5), 2020, 400-408.

Vancouver
Suhartati T, Epriyanti E, Borisha I, Yandri , Suwandi JF, Yuwono SD, Qudus HI, Hadi S. In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus. Rev. Chim.[internet]. 2020 May;71(5):400-408. Available from: https://doi.org/10.37358/RC.20.5.8150


APA 6th edition
Suhartati, T., Epriyanti, E., Borisha, I., Yandri, , Suwandi, J.F., Yuwono, S.D., Qudus, H.I. & Hadi, S. (2020). In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus. Revista de Chimie, 71(5), 400-408. https://doi.org/10.37358/RC.20.5.8150


Harvard
Suhartati, T., Epriyanti, E., Borisha, I., Yandri, , Suwandi, J.F., Yuwono, S.D., Qudus, H.I., Hadi, S. (2020). 'In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus', Revista de Chimie, 71(5), pp. 400-408. https://doi.org/10.37358/RC.20.5.8150


IEEE
T. Suhartati, E. Epriyanti, I. Borisha, Yandri, J.F. Suwandi, S.D. Yuwono, H.I. Qudus, S. Hadi, "In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus". Revista de Chimie, vol. 71, no. 5, pp. 400-408, 2020. [online]. https://doi.org/10.37358/RC.20.5.8150


Text
Tati Suhartati, Eka Epriyanti, Inggit Borisha, Yandri, Jhons F. Suwandi, Suripto D. Yuwono, Hardoko I. Qudus, Sutopo Hadi,
In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus,
Revista de Chimie,
Volume 71, Issue 5,
2020,
Pages 400-408,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.5.8150.
(https://revistadechimie.ro/Articles.asp?ID=8150)
Keywords: antimalarial; artocarpin; artonin M; A. altilis; A. kemando


RIS
TY - JOUR
T1 - In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus
A1 - Suhartati, Tati
A2 - Epriyanti, Eka
A3 - Borisha, Inggit
A4 - Yandri,
A5 - Suwandi, Jhons F.
A6 - Yuwono, Suripto D.
A7 - Qudus, Hardoko I.
A8 - Hadi, Sutopo
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 5
SP - 400
EP - 408
UR - https://doi.org/10.37358/RC.20.5.8150
KW - antimalarial
KW - artocarpin
KW - artonin M
KW - A. altilis
KW - A. kemando
ER -


BibTex
@article{RevCh2020P400,
author = {Suhartati Tati and Epriyanti Eka and Borisha Inggit and Yandri and Suwandi Jhons F. and Yuwono Suripto D. and Qudus Hardoko I. and Hadi Sutopo},
title = {In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus},
journal = {Revista de Chimie},
volume = {71},
number = {5},
pages = {400-408},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.5.8150},
url = {https://revistadechimie.ro/Articles.asp?ID=8150}
}
 
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