Tati Suhartati, Eka Epriyanti, Inggit Borisha, Yandri, Jhons F. Suwandi, Suripto D. Yuwono, Hardoko I. Qudus, Sutopo Hadi
In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus
Abstract:
The derivative of flavonoid compounds, artocarpin (1) and artonin M (2), were isolated from the root wood of Artocarpus altilis and from the root bark of A. kemando, respectively. Both plants originated from Lampung, Indonesia. The structure of the two compounds has been carefully determined by physical method and spectroscopy techniques of UV, IR, and NMR. The in vivo antimalarial test of artocarpin showed very good Plasmodium activity in female mice, with ED50 value of 34.88 mg/kg body weight (kgBW), whereas the in vitro antimalarial test of artonin M showed very strong activity with IC50 of 0.3 μg/mL (5.967 x 10-7 M).
Keywords: antimalarial; artocarpin; artonin M; A. altilis; A. kemando
Cite this article as: SUHARTATI, T., EPRIYANTI, E., BORISHA, I., YANDRI, , SUWANDI, J.F., YUWONO, S.D., QUDUS, H.I., HADI, S., In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus, Rev. Chim., 71(5), 2020, 400-408.
Vancouver Suhartati T, Epriyanti E, Borisha I, Yandri , Suwandi JF, Yuwono SD, Qudus HI, Hadi S. In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus. Rev. Chim.[internet]. 2020 May;71(5):400-408. Available from: https://doi.org/10.37358/RC.20.5.8150
APA 6th edition Suhartati, T., Epriyanti, E., Borisha, I., Yandri, , Suwandi, J.F., Yuwono, S.D., Qudus, H.I. & Hadi, S. (2020). In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus. Revista de Chimie, 71(5), 400-408. https://doi.org/10.37358/RC.20.5.8150
Harvard Suhartati, T., Epriyanti, E., Borisha, I., Yandri, , Suwandi, J.F., Yuwono, S.D., Qudus, H.I., Hadi, S. (2020). 'In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus', Revista de Chimie, 71(5), pp. 400-408. https://doi.org/10.37358/RC.20.5.8150
IEEE T. Suhartati, E. Epriyanti, I. Borisha, Yandri, J.F. Suwandi, S.D. Yuwono, H.I. Qudus, S. Hadi, "In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus". Revista de Chimie, vol. 71, no. 5, pp. 400-408, 2020. [online]. https://doi.org/10.37358/RC.20.5.8150
Text Tati Suhartati, Eka Epriyanti, Inggit Borisha, Yandri, Jhons F. Suwandi, Suripto D. Yuwono, Hardoko I. Qudus, Sutopo Hadi, In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus, Revista de Chimie, Volume 71, Issue 5, 2020, Pages 400-408, ISSN 2668-8212, https://doi.org/10.37358/RC.20.5.8150. (https://revistadechimie.ro/Articles.asp?ID=8150) Keywords: antimalarial; artocarpin; artonin M; A. altilis; A. kemando
RIS TY - JOUR T1 - In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus A1 - Suhartati, Tati A2 - Epriyanti, Eka A3 - Borisha, Inggit A4 - Yandri, A5 - Suwandi, Jhons F. A6 - Yuwono, Suripto D. A7 - Qudus, Hardoko I. A8 - Hadi, Sutopo JF - Revista de Chimie JO - Rev. Chim. PB - Revista de Chimie SRL SN - 2668-8212 Y1 - 2020 VL - 71 IS - 5 SP - 400 EP - 408 UR - https://doi.org/10.37358/RC.20.5.8150 KW - antimalarial KW - artocarpin KW - artonin M KW - A. altilis KW - A. kemando ER -
BibTex @article{RevCh2020P400, author = {Suhartati Tati and Epriyanti Eka and Borisha Inggit and Yandri and Suwandi Jhons F. and Yuwono Suripto D. and Qudus Hardoko I. and Hadi Sutopo}, title = {In Vivo Antimalarial Test of Artocarpin and in vitro Antimalarial Test of Artonin M Isolated from Artocarpus}, journal = {Revista de Chimie}, volume = {71}, number = {5}, pages = {400-408}, year = {2020}, issn = {2668-8212}, doi = {https://doi.org/10.37358/RC.20.5.8150}, url = {https://revistadechimie.ro/Articles.asp?ID=8150} }
