ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHOR'S PAGE NEWS, EVENTS CONTACT
REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

REVISTA DE CHIMIE Latest Issue

LATEST ISSUE >>>

   Volume 75, 2024
   Volume 74, 2023
   Volume 73, 2022
   Volume 72, 2021
   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
 
<<<< back

Revista de Chimie (Rev. Chim.), Year 2020, Volume 71, Issue 5, 450-461

https://doi.org/10.37358/RC.20.5.8157

Maria Iuliana Gruia, Serban Marinescu, Dragos Predescu, George Jinescu, Bogdan Socea, Ion Gruia

Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors

Abstract:

Colorectal cancer (CRC) is one of the most common human malignancies, affecting one of 20 persons in areas with high socio-economic standard. In Romania, the frequency of colorectal cancer is growing rapidly placing the country among countries with an average incidence of the disease. There are some etiologic factors involved and treatment of disease is carried out after proper staging. Biochemical mechanisms underlying malignant transformation in colorectal cancer are not all fully understood, therefore our work trying to enter in the path of oxygen metabolism at patients surgically treated. The aim of the study is to follow the production of active metabolites of oxygen, in the dynamics of the surgical procedure, and how the endogenous natural protection systems are activated, following the invasive procedure. Oxidative stress biochemistry assays, realized before and after surgical excision showed a direct relationship between the production of reactive oxygen species and the presence of tumor, without being able to distinguish exactly if malignant tissue is able to induce oxidative stress, or the latter occurs due to neoplastic changes. Based on the results we can say with certainty that the reactive oxygen species ROS primary attack occurs in the lipids, and then the proteins, following activation of endogenous antioxidant defence.
Keywords:
reactive oxygen species; oxidative stress; endogenous antioxidant defence; plasma malondialdehyde marker; thyol group; ceruloplasmin; colorectal cancer

Issue: 2020, Volume 71, Issue 5
Pages: 450-461
Publication date: 2020/5/29
https://doi.org/10.37358/RC.20.5.8157
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
GRUIA, M.I., MARINESCU, S., PREDESCU, D., JINESCU, G., SOCEA, B., GRUIA, I., Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors, Rev. Chim., 71(5), 2020, 450-461.

Vancouver
Gruia MI, Marinescu S, Predescu D, Jinescu G, Socea B, Gruia I. Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors. Rev. Chim.[internet]. 2020 May;71(5):450-461. Available from: https://doi.org/10.37358/RC.20.5.8157


APA 6th edition
Gruia, M.I., Marinescu, S., Predescu, D., Jinescu, G., Socea, B. & Gruia, I. (2020). Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors. Revista de Chimie, 71(5), 450-461. https://doi.org/10.37358/RC.20.5.8157


Harvard
Gruia, M.I., Marinescu, S., Predescu, D., Jinescu, G., Socea, B., Gruia, I. (2020). 'Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors', Revista de Chimie, 71(5), pp. 450-461. https://doi.org/10.37358/RC.20.5.8157


IEEE
M.I. Gruia, S. Marinescu, D. Predescu, G. Jinescu, B. Socea, I. Gruia, "Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors". Revista de Chimie, vol. 71, no. 5, pp. 450-461, 2020. [online]. https://doi.org/10.37358/RC.20.5.8157


Text
Maria Iuliana Gruia, Serban Marinescu, Dragos Predescu, George Jinescu, Bogdan Socea, Ion Gruia,
Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors,
Revista de Chimie,
Volume 71, Issue 5,
2020,
Pages 450-461,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.5.8157.
(https://revistadechimie.ro/Articles.asp?ID=8157)
Keywords: reactive oxygen species; oxidative stress; endogenous antioxidant defence; plasma malondialdehyde marker; thyol group; ceruloplasmin; colorectal cancer


RIS
TY - JOUR
T1 - Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors
A1 - Gruia, Maria Iuliana
A2 - Marinescu, Serban
A3 - Predescu, Dragos
A4 - Jinescu, George
A5 - Socea, Bogdan
A6 - Gruia, Ion
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 5
SP - 450
EP - 461
UR - https://doi.org/10.37358/RC.20.5.8157
KW - reactive oxygen species
KW - oxidative stress
KW - endogenous antioxidant defence
KW - plasma malondialdehyde marker
KW - thyol group
KW - ceruloplasmin
KW - colorectal cancer
ER -


BibTex
@article{RevCh2020P450,
author = {Gruia Maria Iuliana and Marinescu Serban and Predescu Dragos and Jinescu George and Socea Bogdan and Gruia Ion},
title = {Oxidative Stress Level in Onco-Surgical Treatment Dynamics at Patients with Malignant Colo-Rectal Tumors},
journal = {Revista de Chimie},
volume = {71},
number = {5},
pages = {450-461},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.5.8157},
url = {https://revistadechimie.ro/Articles.asp?ID=8157}
}
 
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Paper Drafting
 * Paper Template
 * Ethical Statement
 * Paper Submission
Ghidul Autorului (ro)
Submit Paper
Author's Page
Publishing Ethics
Peer Review Process
Open Access & Archiving Policy
 Search Authors
 LATEST NEWS
REvista de Chimie NUMAR OMAGIAL PETRU PONI.. detalii
REvista de Chimie Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
dictionar English-Romanian Dictionary for Mechanical Engineering
(download pdf)
  News, Events
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License
 Conferences of Contemporary
 Chemistry
 Biblioteca Chimiei
 Materiale Plastice