Synthesis, Structural Characterization and Biological Studies  of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid

Rehman, Summia; Imran, Muhammad; Kanwal, Ayesha; Latif, Shoomaila; Akbar, Fiza; Mitu, Liviu

Summia Rehman, Muhammad Imran, Ayesha Kanwal, Shoomaila Latif, Fiza Akbar, Liviu Mitu

Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid

Abstract:

Carboxylate functionalized ligand (LH) was synthesized as a result of reaction between maleic anhydride and 2-aminothiazole. This ligand was further reacted with Co(II), Ni(II), Cu(II), Zn(II) and Bi(III) ions to yield respective metal complexes. The structural aspects were studied using FTIR, UV-Visible and 1H-NMR spectroscopy. Non-electrolytic behavior was revealed by the conductivity measurements. Except Bi(III) being octahedral, all other complexes prepared are tetrahedral in geometry. Ligand (LH) and its metal complexes were also investigated for their in vitro antibacterial and antifungal activities. All the complexes exhibited significant antibacterial activity but non-significant antifungal activity.

Keywords:
Aminothiazole; Metal complexes; Spectroscopic characterization; Antibacterial; Antifungal

Issue: 2020, Volume 71, Issue 6

Pages: 75-81

Publication date: 2020/7/1

https://doi.org/10.37358/RC.20.6.8172

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Citation Styles

Cite this article as:
REHMAN, S., IMRAN, M., KANWAL, A., LATIF, S., AKBAR, F., MITU, L., Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid, Rev. Chim., 71(6), 2020, 75-81.

Vancouver
Rehman S, Imran M, Kanwal A, Latif S, Akbar F, Mitu L. Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid. Rev. Chim.[internet]. 2020 Jun;71(6):75-81. Available from: https://doi.org/10.37358/RC.20.6.8172

APA 6th edition
Rehman, S., Imran, M., Kanwal, A., Latif, S., Akbar, F. & Mitu, L. (2020). Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid. Revista de Chimie, 71(6), 75-81. https://doi.org/10.37358/RC.20.6.8172

Harvard
Rehman, S., Imran, M., Kanwal, A., Latif, S., Akbar, F., Mitu, L. (2020). 'Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid', Revista de Chimie, 71(6), pp. 75-81. https://doi.org/10.37358/RC.20.6.8172

IEEE
S. Rehman, M. Imran, A. Kanwal, S. Latif, F. Akbar, L. Mitu, "Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid". Revista de Chimie, vol. 71, no. 6, pp. 75-81, 2020. [online]. https://doi.org/10.37358/RC.20.6.8172

Text
Summia Rehman, Muhammad Imran, Ayesha Kanwal, Shoomaila Latif, Fiza Akbar, Liviu Mitu,
Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid,
Revista de Chimie,
Volume 71, Issue 6,
2020,
Pages 75-81,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.6.8172.
(https://revistadechimie.ro/Articles.asp?ID=8172)
Keywords: Aminothiazole; Metal complexes; Spectroscopic characterization; Antibacterial; Antifungal

RIS
TY - JOUR
T1 - Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid
A1 - Rehman, Summia
A2 - Imran, Muhammad
A3 - Kanwal, Ayesha
A4 - Latif, Shoomaila
A5 - Akbar, Fiza
A6 - Mitu, Liviu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 6
SP - 75
EP - 81
UR - https://doi.org/10.37358/RC.20.6.8172
KW - Aminothiazole
KW - Metal complexes
KW - Spectroscopic characterization
KW - Antibacterial
KW - Antifungal
ER -

BibTex
@article{RevCh2020P75,
author = {Rehman Summia and Imran Muhammad and Kanwal Ayesha and Latif Shoomaila and Akbar Fiza and Mitu Liviu},
title = {Synthesis, Structural Characterization and Biological Studies of Metal Complexes with (E)-4-oxo-4-(thiazol-2-ylamino)but-2-enoic Acid},
journal = {Revista de Chimie},
volume = {71},
number = {6},
pages = {75-81},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.6.8172},
url = {https://revistadechimie.ro/Articles.asp?ID=8172}
}

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