The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe

Ungurianu, Sorin; Trus, Constantin; Enciu, Roxana-Rosmary

Sorin Ungurianu, Constantin Trus, Roxana-Rosmary Enciu

The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe

Abstract:

It is already known from a variety of previous reports that an independent brain renin-angiotensin system (RAS) exists, completely separated from the one in the periphery. This independent brain RAS has all the precursors and the enzymatic structures necessary for the generation of the angiotensin peptides. Thus, in the last few years various groups started focusing on the more central effects of less known angiotensins (e.g in comparison with Angiotensin (Ang) II), namely Ang III, Ang IV, Ang-(1-7) or Ang 5-8. One of these newly emerging angiotensins which has become an increased center of interest in many studies is Ang-(1-7), which is a heptapeptide previously described especially for its opposite effects to Ang II, in the peripheral vascular area, but also described for some opposite central functions vs. Ang II. These aspects are completed with the fact that it was recently suggested that the renin-angiotensin system could modulate the oxidative stress metabolism, and also it seems that the manifestations of Angiotensin-(1-7) on the basal oxidative stress status are contradictory, with a variety of reports describing controversial (e.g. both pro-oxidant and antioxidant actions) effects for this heptapeptide. Our results presented here are confirming a possible antioxidant effect of Ang-(1-7) administration on rat, as shown by the increased levels of antioxidant enzymes from the temporal lobe (superoxide dismutase and glutathione peroxidase) and decreased levels of malondialdehyde, as an important lipid peroxidation parameter.

Keywords:
angiotensin-(1-7); oxidative stress; superoxide dismutase; glutathione peroxidase; malondialdehyde

Issue: 2020, Volume 71, Issue 6

Pages: 307-311

Publication date: 2020/7/1

https://doi.org/10.37358/RC.20.6.8196

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
UNGURIANU, S., TRUS, C., ENCIU, R., The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe, Rev. Chim., 71(6), 2020, 307-311.

Vancouver
Ungurianu S, Trus C, Enciu R. The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe. Rev. Chim.[internet]. 2020 Jun;71(6):307-311. Available from: https://doi.org/10.37358/RC.20.6.8196

APA 6th edition
Ungurianu, S., Trus, C. & Enciu, R. (2020). The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe. Revista de Chimie, 71(6), 307-311. https://doi.org/10.37358/RC.20.6.8196

Harvard
Ungurianu, S., Trus, C., Enciu, R. (2020). 'The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe', Revista de Chimie, 71(6), pp. 307-311. https://doi.org/10.37358/RC.20.6.8196

IEEE
S. Ungurianu, C. Trus, R. Enciu, "The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe". Revista de Chimie, vol. 71, no. 6, pp. 307-311, 2020. [online]. https://doi.org/10.37358/RC.20.6.8196

Text
Sorin Ungurianu, Constantin Trus, Roxana-Rosmary Enciu,
The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe,
Revista de Chimie,
Volume 71, Issue 6,
2020,
Pages 307-311,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.6.8196.
(https://revistadechimie.ro/Articles.asp?ID=8196)
Keywords: angiotensin-(1-7); oxidative stress; superoxide dismutase; glutathione peroxidase; malondialdehyde

RIS
TY - JOUR
T1 - The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe
A1 - Ungurianu, Sorin
A2 - Trus, Constantin
A3 - Enciu, Roxana-Rosmary
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 6
SP - 307
EP - 311
UR - https://doi.org/10.37358/RC.20.6.8196
KW - angiotensin-(1-7)
KW - oxidative stress
KW - superoxide dismutase
KW - glutathione peroxidase
KW - malondialdehyde
ER -

BibTex
@article{RevCh2020P307,
author = {Ungurianu Sorin and Trus Constantin and Enciu Roxana-Rosmary},
title = {The Biochemical Effects of Angiotensin-(1-7) on the Oxidative Stress Metabolism and Their Specific Parameters from the Temporal Lobe},
journal = {Revista de Chimie},
volume = {71},
number = {6},
pages = {307-311},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.6.8196},
url = {https://revistadechimie.ro/Articles.asp?ID=8196}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)