Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues

Jurja, Sanda; Mehedinti, Mihaela; Sirbu, Rodica; Coman, Malina; Cadar, Emin

Sanda Jurja, Mihaela Mehedinti, Rodica Sirbu, Malina Coman, Emin Cadar

Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues

Abstract:

Relapsing polychondritis (RP), falls into the category of rare diseases. The true incidence and prevalence of this rare disease is unknown. The ocular implications in relapsing polychondritis (RP) are numerous and variable, including mainly inflammation in different structures of the eye. As a complication of this inflammatory condition, a closed secondary angle glaucoma has been described. The purpose of our work is to highlight the diversity of ocular determinations of the same rare disease, including different types of glaucoma that may occur under the same circumstances and to make a detailed analysis of chemical therapies based on drug treatment pathways. The paper includes a report of the cases series admitted to the Clinic of Ophthalmology in St. Andrew Emergency Clinical Hospital, Constanta, between 2007 and 2018, cases analyzed and compared with international literature. One of the cases is a 43-year-old male patient with bilateral open-angle bilateral glaucoma. Other cases with RP, are patients of 41 and 46 years old, respectively, presented with unilateral episcleritis. This case series report aims to show that RP can associate even more protean ocular manifestations than already discussed in the literature, with specific chemical therapies and to emphasize the need for team approach and ophthalmological monitoring in the care of RP patients with chemical therapy (drug treatment) for each patient.

Keywords:
chemical therapy; steroid; relapsing polychondritis; inflammation; glaucoma

Issue: 2020, Volume 71, Issue 8

Pages: 284-291

Publication date: 2020/8/31

https://doi.org/10.37358/RC.20.8.8301

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
JURJA, S., MEHEDINTI, M., SIRBU, R., COMAN, M., CADAR, E., Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues, Rev. Chim., 71(8), 2020, 284-291.

Vancouver
Jurja S, Mehedinti M, Sirbu R, Coman M, Cadar E. Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues. Rev. Chim.[internet]. 2020 Aug;71(8):284-291. Available from: https://doi.org/10.37358/RC.20.8.8301

APA 6th edition
Jurja, S., Mehedinti, M., Sirbu, R., Coman, M. & Cadar, E. (2020). Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues. Revista de Chimie, 71(8), 284-291. https://doi.org/10.37358/RC.20.8.8301

Harvard
Jurja, S., Mehedinti, M., Sirbu, R., Coman, M., Cadar, E. (2020). 'Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues', Revista de Chimie, 71(8), pp. 284-291. https://doi.org/10.37358/RC.20.8.8301

IEEE
S. Jurja, M. Mehedinti, R. Sirbu, M. Coman, E. Cadar, "Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues". Revista de Chimie, vol. 71, no. 8, pp. 284-291, 2020. [online]. https://doi.org/10.37358/RC.20.8.8301

Text
Sanda Jurja, Mihaela Mehedinti, Rodica Sirbu, Malina Coman, Emin Cadar,
Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues,
Revista de Chimie,
Volume 71, Issue 8,
2020,
Pages 284-291,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.8.8301.
(https://revistadechimie.ro/Articles.asp?ID=8301)
Keywords: chemical therapy; steroid; relapsing polychondritis; inflammation; glaucoma

RIS
TY - JOUR
T1 - Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues
A1 - Jurja, Sanda
A2 - Mehedinti, Mihaela
A3 - Sirbu, Rodica
A4 - Coman, Malina
A5 - Cadar, Emin
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 8
SP - 284
EP - 291
UR - https://doi.org/10.37358/RC.20.8.8301
KW - chemical therapy
KW - steroid
KW - relapsing polychondritis
KW - inflammation
KW - glaucoma
ER -

BibTex
@article{RevCh2020P284,
author = {Jurja Sanda and Mehedinti Mihaela and Sirbu Rodica and Coman Malina and Cadar Emin},
title = {Importance of Chemical Therapy in Relapsing Polychondritis - a Disease with Impact on the Eye Tissues},
journal = {Revista de Chimie},
volume = {71},
number = {8},
pages = {284-291},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.8.8301},
url = {https://revistadechimie.ro/Articles.asp?ID=8301}
}

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