Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide

Junmei, Zhang; Ahui, Zhu; Yan, Wang; Linbo, Hu; Wenhui, Xu; Zhenya, Duan

Zhang Junmei, Zhu Ahui, Wang Yan, Hu Linbo, Xu Wenhui, Duan Zhenya

Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide

Abstract:

Potassium isopropoxide, involved in the cycle reaction of the intermediate dehydroester, is an important coupling agent in the production of drug pipemidic acid tablets. Current production problems of potassium isopropoxide by alkali method are the long period, the low productivity and the high energy consumption. To solve these problems, the reactive distillation production process of potassium isopropoxide was studied by simulation calculation and pilot experiment. The results show that the production process of potassium isopropanol is influenced by the separation efficiency and the reaction rate. The number of suitable theoretical plates for the column of azeotropic distillation is 14. The dissolution of solid potassium hydroxide is promoted and the reaction rate is increased, when a small amount of water is added to the raw material. It is found that the water content in the reflux organic phase can be reduced by lowering the liquid temperature in the condenser. It is also observed that suitable process conditions and the new type phase splitter can greatly reduced the production time of each batch of potassium isopropoxide.

Keywords:
potassium isopropoxide; reactive distillation; alkaline

Issue: 2020, Volume 71, Issue 9

Pages: 153-161

Publication date: 2020/9/5

https://doi.org/10.37358/RC.20.9.8325

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
JUNMEI, Z., AHUI, Z., YAN, W., LINBO, H., WENHUI, X., ZHENYA, D., Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide, Rev. Chim., 71(9), 2020, 153-161.

Vancouver
Junmei Z, Ahui Z, Yan W, Linbo H, Wenhui X, Zhenya D. Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide. Rev. Chim.[internet]. 2020 Sep;71(9):153-161. Available from: https://doi.org/10.37358/RC.20.9.8325

APA 6th edition
Junmei, Z., Ahui, Z., Yan, W., Linbo, H., Wenhui, X. & Zhenya, D. (2020). Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide. Revista de Chimie, 71(9), 153-161. https://doi.org/10.37358/RC.20.9.8325

Harvard
Junmei, Z., Ahui, Z., Yan, W., Linbo, H., Wenhui, X., Zhenya, D. (2020). 'Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide', Revista de Chimie, 71(9), pp. 153-161. https://doi.org/10.37358/RC.20.9.8325

IEEE
Z. Junmei, Z. Ahui, W. Yan, H. Linbo, X. Wenhui, D. Zhenya, "Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide". Revista de Chimie, vol. 71, no. 9, pp. 153-161, 2020. [online]. https://doi.org/10.37358/RC.20.9.8325

Text
Zhang Junmei, Zhu Ahui, Wang Yan, Hu Linbo, Xu Wenhui, Duan Zhenya,
Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide,
Revista de Chimie,
Volume 71, Issue 9,
2020,
Pages 153-161,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.9.8325.
(https://revistadechimie.ro/Articles.asp?ID=8325)
Keywords: potassium isopropoxide; reactive distillation; alkaline

RIS
TY - JOUR
T1 - Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide
A1 - Junmei, Zhang
A2 - Ahui, Zhu
A3 - Yan, Wang
A4 - Linbo, Hu
A5 - Wenhui, Xu
A6 - Zhenya, Duan
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 9
SP - 153
EP - 161
UR - https://doi.org/10.37358/RC.20.9.8325
KW - potassium isopropoxide
KW - reactive distillation
KW - alkaline
ER -

BibTex
@article{RevCh2020P153,
author = {Junmei Zhang and Ahui Zhu and Yan Wang and Linbo Hu and Wenhui Xu and Zhenya Duan},
title = {Process Optimization and Experimental Study on the Alkaline Production Process of Potassium Isopropoxide},
journal = {Revista de Chimie},
volume = {71},
number = {9},
pages = {153-161},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.9.8325},
url = {https://revistadechimie.ro/Articles.asp?ID=8325}
}

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