Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice

Moisa, Corina; Bungau, Simona; Behl, Tapan; Banica, Florin; Purza, Lavinia; Moleriu, Radu Dumitru; Cadar, Oana; Fratila, Ovidiu; Tit, Delia Mirela

Corina Moisa, Simona Bungau, Tapan Behl, Florin Banica, Lavinia Purza, Radu Dumitru Moleriu, Oana Cadar, Ovidiu Fratila, Delia Mirela Tit

Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice

Abstract:

This research establishes the relationship between the influence of the stability of 6 magnesium compounds on their cellular uptake and focuses on the comparation between them, finding out which is the magnesium compound with the best bioavailability, depending on the stability. Mg2+ was dosed from tissues taken from various mice organs after the administration of compounds containing it, during the shelf life of the compounds, respectively at 6/12 months after their expiration. Different quantities of substances were also used - 25/50/100/200/300 mg/day/mouse, in groups of 2 mice for each dose. The samples were administered by gavage, following in parallel the possible side effects that may occur. During the shelf life of the compounds and at 6 months after expiration, in all organs, the lowest value was obtained for magnesium oxide and the highest value was detected for magnesium citrate. At 12 months after expiration, in all organs, the lowest/highest value was obtained in the case of oxide/orotate, respectively. It was found that the highest concentration of magnesium is stored in the spleen and lowest in lungs. The data obtained demonstrated a good stability of the tested substances (indicated by maintaining the cellular uptake rate) even 6 months after the expiration date.

Keywords:
magnesium compounds; stability; absorption; shelf life; therapeutic efficiency

Issue: 2020, Volume 71, Issue 10

Pages: 200-211

Publication date: 2020/11/3

https://doi.org/10.37358/RC.20.10.8364

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
MOISA, C., BUNGAU, S., BEHL, T., BANICA, F., PURZA, L., MOLERIU, R.D., CADAR, O., FRATILA, O., TIT, D.M., Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice, Rev. Chim., 71(10), 2020, 200-211.

Vancouver
Moisa C, Bungau S, Behl T, Banica F, Purza L, Moleriu RD, Cadar O, Fratila O, Tit DM. Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice. Rev. Chim.[internet]. 2020 Oct;71(10):200-211. Available from: https://doi.org/10.37358/RC.20.10.8364

APA 6th edition
Moisa, C., Bungau, S., Behl, T., Banica, F., Purza, L., Moleriu, R.D.,... Tit, D.M. (2020). Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice. Revista de Chimie, 71(10), 200-211. https://doi.org/10.37358/RC.20.10.8364

Harvard
Moisa, C., Bungau, S., Behl, T., Banica, F., Purza, L., Moleriu, R.D., Cadar, O., Fratila, O., Tit, D.M. (2020). 'Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice', Revista de Chimie, 71(10), pp. 200-211. https://doi.org/10.37358/RC.20.10.8364

IEEE
C. Moisa, S. Bungau, T. Behl, F. Banica, L. Purza, R.D. Moleriu, O. Cadar, O. Fratila, D.M. Tit, "Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice". Revista de Chimie, vol. 71, no. 10, pp. 200-211, 2020. [online]. https://doi.org/10.37358/RC.20.10.8364

Text
Corina Moisa, Simona Bungau, Tapan Behl, Florin Banica, Lavinia Purza, Radu Dumitru Moleriu, Oana Cadar, Ovidiu Fratila, Delia Mirela Tit,
Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice,
Revista de Chimie,
Volume 71, Issue 10,
2020,
Pages 200-211,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.10.8364.
(https://revistadechimie.ro/Articles.asp?ID=8364)
Keywords: magnesium compounds; stability; absorption; shelf life; therapeutic efficiency

RIS
TY - JOUR
T1 - Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice
A1 - Moisa, Corina
A2 - Bungau, Simona
A3 - Behl, Tapan
A4 - Banica, Florin
A5 - Purza, Lavinia
A6 - Moleriu, Radu Dumitru
A7 - Cadar, Oana
A8 - Fratila, Ovidiu
A9 - Tit, Delia Mirela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 10
SP - 200
EP - 211
UR - https://doi.org/10.37358/RC.20.10.8364
KW - magnesium compounds
KW - stability
KW - absorption
KW - shelf life
KW - therapeutic efficiency
ER -

BibTex
@article{RevCh2020P200,
author = {Moisa Corina and Bungau Simona and Behl Tapan and Banica Florin and Purza Lavinia and Moleriu Radu Dumitru and Cadar Oana and Fratila Ovidiu and Tit Delia Mirela},
title = {Aspects Regarding the Relationship Between the Stability of Six Magnesium Compounds and their Cellular Uptake in Mice},
journal = {Revista de Chimie},
volume = {71},
number = {10},
pages = {200-211},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.10.8364},
url = {https://revistadechimie.ro/Articles.asp?ID=8364}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)